RECENT PUBLICATIONS

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• Photo-Switched Catalytic Amyloids, Shubhra Kanti Bhaumik, Sisira Mambram Kunnath, Elad Arad, Einat Nativ-Roth, Arunavo Chatterjee, Albert Batushansky, Nitzan Shauloff, Hanna Rapaport, Raz Jelinek, Small, 22: e76166.

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• Allosteric amyloid catalysis by coiled coil fibrils, Sisira Mambram Kunnath, Elad Arad, Ran Zalk, Itamar Kass, Anat Shahar, Albert Batushansky, Hanna Rapaport, Raz Jelinek, Nat Commun 2025,16, 5071.

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• Assessing the Catalytic Role of Native Glucagon Amyloid Fibrils, Ashim Nandi, Aoxuan Zhang, Elad Arad, Raz Jelinek, Arieh Warshel, ACS Catalysis, 2024, 14, 4656-4664.

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• Catalytic physiological amyloids, Elad Arad, Raz Jelinek, Methods in Enzymology, 2024, vol. 697, 77-112.

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• Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics, Elad Arad, Kasper B. Pedersen, Orit Malka, Sisira Mambram Kunnath, Nimrod Golan, Polina Aibinder, Birgit Schiøtt, Hanna Rapaport, Meytal Landau, Raz Jelinek, Nature Communications, 2023,14, 8198.

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• Synergistic activity of anti-cancer polyphenols embedded in amphiphilic dendrimer nanoparticles, Shani Ben-Zichri, May Meltzer, Shiran Lacham-Hartman, Sofiya Kolusheva, Uzi Hadad, Niv Papo, Raz Jelinek, ACS Applied Polymer Materials, 2022, 4, 12, 8913-8925.

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• Native glucagon amyloids catalyze key metabolic reactions, Elad Arad, Gal Yosefi, Sofiya Kolusheva, Ronit Bitton, Hanna Rapaport, Raz Jelinek, ACS Nano, 2022, 16, 8, 12889-12899.

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• Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells, Shani Ben-Zichri, Sathish Rajendran, Susanta K. Bhunia, Raz Jelinek, Bioconjugate Chemistry, 2022, 33, 9, 1663-1671.  

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• Catalytic amyloids, Elad Arad, Raz Jelinek, Trends in Chemistry, 2022, 4 (10), P907-917.

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• Amyloid fishing: β-amyloid adsorption using tailor-made coated titania nanoparticles, Elad Arad, Raz Jelinek, Hanna Rapaport, Colloids and Surfaces B: Biointerfaces, 2022, 212, 112374.

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• Bcl-2-homology-only pro-apoptotic peptides modulate β-amyloid aggregation and toxicity, Shani Ben- Zichri, Ravit Malishev, Ofek Oren, Daniel N. Bloch, Ran Taube, Niv Papo, Raz Jelinek, ACS Chemical Neuroscience, 2021, 12, 4554-4563.

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• Dual concentration-dependent effect of Ascorbic acid on PAP(248-286) amyloid formation and SEVI-mediated HIV infection, Satabdee Mohapatra, Guru Krishna Kumar Viswanathan, Lukas Wettstein, Elad Arad, Ashim Paul, Raz Jelinek, Jan Münch, Daniel Segal, RSC Chemical Biology, 2021, 2, 1534-1545.

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• beta-Amyloid fibrils catalyze neurotransmitter degradation, Elad Arad, Avigail Baruch-Leshem, Hanna Rapaport, Raz Jelinek, Chem Catalysis, 2021, 1, 908-922.

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• A Mechanism for the Inhibition of tau Neurotoxicity: Studies with Artificial Membranes, Isolated Mitochondria and Intact Cells, Segev Naveh Tassa, Shani Ben Zichri, Shiran Lacham-Hartman, Ofek Oren, Zeev Slobodnik, Ekaterina Eremenko, Debra Toiber, Raz Jelinek, Niv Papo, ACS Chemical Neuroscience, 2021, 12, 9, 1563-1577.

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• Inhibition of Staphylococcus aureus Biofilm-forming Functional Amyloid by Molecular Tweezers, Ravit Malishev, Nir Salinas, James Gibson, Angela Bailey Eden, Joel Mieres-Perez, Yasser Ruiz-Blanco, Orit Malka, Sofiya Kolusheva, Frank-Gerrit Klärner, Thomas Schrader, Elsa Sanchez-Garcia, Chunyu Wang, Meytal Landau, Gal Bitan, Raz Jelinek, Cell Chemical Biology, 2021, 28, 1310-1320.e5.

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• Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone-Dopamine hybrid, Ashim Paul, Guru KrishnaKumar Viswanathan, Adi Huber, Elad Arad, Hamutal Engel, Raz Jelinek, Ehud Gazit, Daniel Segal FEBS Journal, 2021, i288, 4267-4290.

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• The Amphibian Antimicrobial Peptide Uperin 3.5 is a Cross-α/Cross-β Chameleon Functional Amyloid, Nir Salinas, Einav Tayeb-Fligelman, Massimo Sammito, Daniel Bloch, Raz Jelinek, Dror Noy, Isabel Uson, and Meytal Landau, PNAS, 2021, 118(3), e2014442118.

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• Mitochondrial membrane transformations in prostate and colon cancers and their biological implications, Shani Ben Zichri, Sofiya Kolusheva, Alexander I Shames, Elina Abaev Schneiderman, Juan L Poggio, David E Stein, Elena Doubijensky, Dan Levy, Zulfiya Orynbayeva, Raz Jelinek, BBA-Biomembranes, 2021, 1863, 183471.

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• The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils, Ravit Malishev, Shani Ben- Zichri, Ofek Oren, Nitzan Shauloff, Ran Taube, Niv Papo, Raz Jelinek, Cellular and Molecular Life Sciences, 2020, 78, 2145-2155. 

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• Tyrosine carbon dots inhibit fibrillation and toxicity of the human Islet amyloid polypeptide, Daniel Bloch, Shani Ben Zichri, Sofiya Kolusheva, Raz Jelinek, Nanoscale Advances, 2020, 13, 5866-5873. (Article selected to appear in a special collection on “Quantum and carbon dots”).

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• Revisiting thioflavin T (ThT) fluorescence as a marker of protein fibrillation – the prominent role of electrostatic interactions, Elad Arad, Hodaya Green, Raz Jelinek, Hanna Rapaport, Journal of Colloids & Interface Science, 2020, 573, 87-95.

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• An Aβ42 double mutant inhibits Aβ42-induced plasma and mitochondrial membrane disruption in artificial membranes, isolated organs and intact cells, Ofek Oren, Shani Ben Zichri, Ran Taube, Raz Jelinek, Niv Papo, ACS Chemical Neuroscience, 2020, 11, 1027-1037.

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• Imaging flow cytometry illuminates new dimensions of prion-protein membrane interactions, Reut Israeli, Sofiya Kolusheva, Uzi Hadad, Raz Jelinek, Biophysical Journal, 2020, 118, 1270-1278.

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• Tryptophan-Glucosamine Conjugates Modulate Tau-Derived PHF6 aggregation at Low concentrations, Ashim Paul, Wen-Hao Li, Guru Viswanathan, Elad Arad, Satabdee Mohapatra, Gao Li, Raz Jelinek, Ehud Gazit, Yanmei Li, Daniel Segal, Chemical Communications, 2019, 55, 14621-14624.

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• Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model, V. Guru KrishnaKumar, Dana Shwartz, Elad Arad, Edward Pichinuk, Hamutal Engel, Avi Raveh, Raz Jelinek, Ehud Gazit, Daniel Segal, Cellular and Molecular Life Sciences, 2019, 77, 2795-2813.

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• Unravelling the role of amino acid sequence order in the assembly and function of the amyloid-β core, Santu Bera, Elad Arad, Lee Schnaider, Shira Shaham-Niv, Valeria Castelletto, Yossef Peretz, Dor Zaguri, Raz Jelinek, Ehud Gazit, Ian Hamley ChemComm, 2019, 55, 8595-8599.

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• Interactions between BIM protein and beta-amyloid may reveal a crucial missing link between Alzheimer's disease and neuronal cell death, Ravit Malishev, Sukhendu Nandi, Dariusz Śmiłowicz, Shamchal Bakavayev, Stanislav Engel, Nir Bujanover, Roi Gazit, Nils Metzler-Nolte, Raz Jelinek, ACS Chemical Neuroscience, 2019, 10, 3555-3564.

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• Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid towards Aggregation of PAP f39 Semen Amyloid, V. Guru KrishnaKumar, Satabdee Mohapatra, Ashim Paul, Elad Arad, Raz Jelinek, Ehud Gazit, Daniel Segal , Molecules, 2019, 23, 3279.

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• Cardiolipin mediates curcumin interactions with mitochondrial membranes, Shani Ben-Zichri, Sofiya Kolushev, Michael Danilenko, Saniya Ossikbayeva, William J. Stabbert, Juan L. Poggio, David E. Stein, Zulfiya Orynbayeva, Raz Jelinek, BBA - Biomembranes, 2019, 1861, 75-82.

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• Chiral modulation of amyloid beta fibrillation and cytotoxicity by enantiomeric carbon dots, Ravit Malishev, Elad Arad, Susanta Kumar Bhunia, Shira Shaham-Niv, Sofiya Kolusheva, Ehud Gazit, Raz Jelinek, Chemical Communications, 2018, 54, 7762-7765.

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• Vesicle-based assays to study membrane interactions of amyloid peptides, Ravit Malishev, Raz Jelinek, Proteins in Misfolding Diseases, Springer Protocols – Methods in Molecular Biology, 2018, 1873, 39-52.

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• Lysine-Derived Carbon Dots for Chiral Inhibition of Prion Peptide Fibril Assembly, Elad Arad, Susanta Kumar Bhunia, Juergen Jopp, Sofiya Kolusheva, Hanna Rapaport, Raz Jelinek, Advanced Therapeutics, 2018, 1, 1800006.

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• Nanoparticles modulate membrane interactions of human Islet amyloid polypeptide (hIAPP), Yossef Peretz, Ravit Malishev, Sofiya Kolusheva, Raz Jelinek, BBA-Biomembranes, 2018, 1860, 1810-1817.

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• Reciprocal Interactions between Membrane Bilayers and Staphylo-coccus aureus PSMα3 Cross-α Amyloid-like Fibrils Provide Mechanistic Insight into Species-specific Cytotoxicity, Ravit Malishev, Einav Tayeb-Fligelman, Shimrit David, Meytal Landau, Raz Jelinek,Journal of Molecular Biology, 2018, 430, 1431-1441.

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• Bacterial model membranes reshape fibrillation of a Bacillus subtilis functional amyloid protein, Ravit Malishev, Razan Abbasi, Raz Jelinek, Liraz Chai*,Biochemistry, 2018, 57, 5230-5238.

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• Membrane Determinants Affect Fibrillation Processes of β-sheet Charged Peptides, Elad Arad, Ravit Malishev, Hanna Rapaport, Raz Jelinek, Biomacromolecules, 2018, 19, 307-314.

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• Bacoside-A, an Indian traditional medicine substance, inhibits beta amyloid cytotoxicity, fibrillation, and membrane interactions, Ravit Malishev, Shira Shaham-Niv, Sofiya Kolusheva, Sukhendu Nandi, Ehud Gazit, Raz Jelinek, ACS Chemical Neuroscience, 2017, 8(4), 884-891.

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• Bacoside-A, an anti-amyloid natural substance, inhibits membrane disruption by the amyloidogenic determinant of prion protein through accelerating fibril formation, R. Malishev, S. Nandi, S. Kolusheva, S. Shaham-Niv, Ehud Gazit, Raz Jelinek, BBA-Biomembranes, 2016, 1858, 2208-2214.

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• Toxicity inhibitors protect lipid membranes from disruption by Aβ42, Ravit Malishev, Sukhendu Nandi, Sofiya Kolusheva, Yael Levi-Kalisman, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan, Raz Jelinek, ACS Chemical Neurosciences, 2015, 6(11), 1860-1869.

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• Lipid Bilayers Significantly Modulate Cross-Fibrillation of Two Distinct Amyloidogenic Peptides, Noga Gal, Ahiud Morag, Sofiya Kolusheva, Roland Winter, Meytal Landau, Raz Jelinek, Journal of the American Chemical Society, 2013, 135, 13582-13589.

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• Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils, Tania Sheynis, Anat Friediger, Wei-Feng Xue, Andrew L. Hellewell, Kevin W. Tipping, Eric W. Hewitt, Sheena E. Radford, Raz Jelinek, Biophysical Journal, 2013, 105, 745-755.

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• Heparin inhibits membrane interactions and lipid-induced fibrillation of a prion amyloidogenic determinant, Ehud Bazar, Tania Sheynis, Jerzy Dorosz, Raz Jelinek, ChemBioChem, 2011, 12, 761-767.